A New(-ish) Antacid Medication - Knowledgeable Provider |...

What this episode covers

The new PCAB Voquenza (vonoprazan) is being marketed as a superior alternative to PPI therapy for acid-related conditions (GERD with or without erosive esophagitis, H. pylori eradication). Are these two mechanisms of action really that different? Jody investigates. References: 1) Prescriber information: https://www.phathompharma.com/wp-content/uploads/VOQUEZNA-tablets-Prescriber-Information.pdf 2) György Miklós Buzás, Dual acid-pump blocking as novel therapeutic approach to treatment of acid-related diseases, Medical Hypotheses, Volume 187, 2024, 111338, ISSN 0306-9877, https://doi.org/10.1016/j.mehy.2024.111338. 3) Katzka DA, Kahrilas PJ. Potassium-Competitive Acid Blocker Suppression of Gastric Acid in Erosive Esophagitis: Is Stronger and Longer Better? Gastroenterology. 2023 Jan;164(1):14-15. doi: 10.1053/j.gastro.2022.10.022. Epub 2022 Oct 28. PMID: 36341738. 4) Shin JM, Sachs G. Pharmacology of proton pump inhibitors. Curr Gastroenterol Rep. 2008 Dec;10(6):528-34. doi: 10.1007/s11894-008-0098-4. PMID: 19006606; PMCID: PMC2855237. 5) Simadibrata DM, Syam AF, Lee YY. A comparison of efficacy and safety of potassium-competitive acid blocker and proton pump inhibitor in gastric acid-related diseases: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2022 Dec;37(12):2217-2228. doi: 10.1111/jgh.16017. Epub 2022 Oct 26. PMID: 36181401; PMCID: PMC10092067. 6) Oshima T, Miwa H. Potent Potassium-competitive Acid Blockers: A New Era for the Treatment of Acid-related Diseases. J Neurogastroenterol Motil. 2018 Jul 30;24(3):334-344. doi: 10.5056/jnm18029. PMID: 29739175; PMCID: PMC6034668

Share this episode

Similar Episodes

🚨 DID YOU KNOW? 🚨Trillionaire Status

Jun 19, 2026 ·18m

Episode #1088: Pointe Mouillee Waterfowl Festival

Jun 19, 2026 ·48m

EP 571 - Metal Annihilation

Jun 19, 2026 ·33m

Episode #1087: Tony’s Conspiracy Corner

Jun 18, 2026 ·136m

Public Land - Washington - Nathan Peterson

Jun 17, 2026 ·62m

🚨 DID YOU KNOW? 🚨Trade Secrets & Patents

Jun 12, 2026 ·17m

Similar Podcasts

The Curds of Wisdom Podcast James and Cole The C.O.W. Podcast is only occasionally about cows. We talk about life, family, farming and funny stories. Sometimes serious topics will arise, and we'll have some very knowledgeable guests on to talk about everything from succession planning to emotional well being to manure handling and anything in between. Explicit Weird Medicine: The Podcast Dr. Steve & Studio71 Since 2007, Weird Medicine has been "the first and still only uncensored medical show in broadcast radio history" on SiriusXM. Now, the same crew that continues to shock, horrify, entertain and inform the satellite airwaves is producing a weekly podcast! This is a medical show for people who would never listen to a medical show on the internet (or anywhere else). If you have a question you'd like answered on the show, call the voicemail line at 347 766 4323 (347 POO HEAD) any time. Remember, Weird Medicine: The Podcast is an entertainment show and Doctor Steve is not your doctor. Always double check anything you hear on this show with your regular medical provider(s). *Warning: Weird Medicine contains extreme language and may not be suitable for younger listeners (actually, it's pretty unsuitable for just about everyone, so listen at your own risk)*We wanna make the podcast even better, help us learn how we can: https://bit.ly/2EcYbu4 Explicit Sarcasm Podcast Sarcasm Podcast We are the “Sarcasm Podcast” We bring our knowledge (and sarcasm) to enlighten you about every day topics. Tune in for our variety of guests ranging from UFC fighters to comedians! Check us out on YouTube for LIVE streamed episodes as well as Instagram and Facebook for funny and knowledgeable content. Explicit I'll Drink to That! Wine Talk Levi Dalton A former sommelier interviews incredibly famous and knowledgeable wine personalities in his tiny apartment. He gets them to talk candidly about their lives and work, and then shares the conversations with you. To see new episodes sooner and to see all of the hundreds of back episodes in your feed, it is important to FOLLOW or SUBSCRIBE the show. It is free to do either, the show is free.Contact info-Email [email protected] for advertising, consulting, speaking, or guest inquiriesInstagram @leviopenswineWebsite illdrinktothatpod.com Explicit

Frequently Asked Questions

How long is this episode of Knowledgeable Provider?

This episode is 11 minutes long.

When was this Knowledgeable Provider episode published?

This episode was published on September 2, 2024.

What is this episode about?

The new PCAB Voquenza (vonoprazan) is being marketed as a superior alternative to PPI therapy for acid-related conditions (GERD with or without erosive esophagitis, H. pylori eradication). Are these two mechanisms of action really that different?...

Can I download this Knowledgeable Provider episode?

Yes, you can download this episode by clicking the download button on the episode player, or subscribe to the podcast in your preferred podcast app for automatic downloads.