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EPISODE · Jul 23, 2026 · 25 MIN

A Paradigm Shift in the Clinical Course of TED

from Experts InSight

In today's episode, host Dr. Amanda Redfern welcomes Dr. Madhura Tamhankar to discuss a new study using IRIS Registry and Komodo Health claims data that upends Rundle's 1940s biphasic model of thyroid eye disease (TED). Drawing on more than 34,000 patients with 5-year median follow-up, Dr. Tamhankar's study found that even among patients with initially mild disease, 1 in 3 progress within 5 years, with rates climbing from 12% at year 1 to 38% by year 8. Dr. Tamhankar reviews the study's methodology and its implications for patient care, including surgical timing, informed consent, and specialist referral. For all episodes or to claim CME credit for selected episodes, visit www.aao.org/podcasts.

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