A Sickness in the Serum, Part 2: The Birth of Immune Complex Disease

from Healio Rheuminations · host Adam J. Brown, MD

The second episode in the series delves into the experiments and observations of Dr. Clemens (Baron) von Pirquet who first proposed that antibodies and antigens join forces to wreak havoc. Brought to you by GSK. Intro :10 Today's episode :26 A recap of the previous episode :43 About Baron von Pirquet 4:40 What's going on in the study of infectious disease and immunology in the early 1900s? 6:41 Writing the paper, "Serum Sickness" 13:13 What are the antibodies doing at that time? 19:10 What happened to Dr. Pirquet? 20:44 Pirquet's medical student, Bela Schick 25:35 Episode wrap-up 27:27 The next episode 27:56 Thanks again for listening! 29:17 Disclosures: Brown reports no relevant financial disclosures. We'd love to hear from you! Send your comments/questions to Dr. Brown at [email protected]. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum References: Shulman ST. J Pediatric Infect Dis Soc. 2017;6:376-379. Silverstein AM. Nat Immunol. 2000;1:453-455.

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