A1C pitfalls

This episode delivers a rigorous evaluation of hemoglobin A1c pitfalls where the marker fails to accurately reflect true glycemia. We examine how altered erythrocyte turnover, hemoglobin variants, and specific clinical conditions distort glycation dynamics independently of plasma glucose levels. Listeners will learn to identify when to suspect inaccurate A1c readings, how conditions like advanced chronic kidney disease or hemoglobinopathies confound data, and when to utilize alternative biomarkers like fructosamine or continuous glucose monitoring metrics instead.