EPISODE · Jul 2, 2025 · 24 MIN
ADDF's Karen Harris: Investing in Alzheimer's Like a VC
from Citeline Podcasts · host Norstella
How is venture philanthropy revolutionizing Alzheimer's drug discovery? We sit down with Karen Harris, CFO at the Alzheimer's Drug Discovery Foundation, to explore their game-changing approach to funding early-stage research. With $370M+ awarded to 765+ programs globally, the ADDF operates like a VC firm—using convertible debt and preferred equity to accelerate breakthrough treatments. Topics: Venture philanthropy vs traditional grants Shift from amyloid to combination therapies Blood-based biomarkers & precision medicine NIH funding cuts impact on research ecosystem Karen brings 20+ years investment banking experience to discuss how strategic capital is changing Alzheimer's research.
What this episode covers
How is venture philanthropy revolutionizing Alzheimer's drug discovery? We sit down with Karen Harris, CFO at the Alzheimer's Drug Discovery Foundation, to explore their game-changing approach to funding early-stage research. With $370M+ awarded to 765+ programs globally, the ADDF operates like a VC firm—using convertible debt and preferred equity to accelerate breakthrough treatments. Topics: Venture philanthropy vs traditional grants Shift from amyloid to combination therapies Blood-based biomarkers & precision medicine NIH funding cuts impact on research ecosystem Karen brings 20+ years investment banking experience to discuss how strategic capital is changing Alzheimer's research.
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ADDF's Karen Harris: Investing in Alzheimer's Like a VC
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