Advanced Skin Cancer: A Case-Based Approach

Focuses on a case-based approach to diagnosing and managing various advanced cutaneous malignancies. The sources are heavily focused on melanoma, discussing its subtypes, staging systems (like AJCC and BWH for cSCC), and treatment protocols, including surgery (WLE, Mohs, SLNB), radiotherapy (TSEBT, focal RT), and systemic therapies such as immunotherapy (PD-1 inhibitors, anti-CTLA-4 agents like nivolumab and ipilimumab) and targeted therapy (BRAF/MEK and hedgehog pathway inhibitors like vismodegib/sonidegib). The text thoroughly examines the management of different cancers, including Cutaneous Lymphoma (MF, PC-ALCL, PCFCL, PC-DLBCL), Kaposi’s Sarcoma (AIDS-associated, iatrogenic), Basal Cell Carcinoma (laBCC, BCNS), Dermatofibrosarcoma Protuberans (DFSP), and Merkel Cell Carcinoma (MCC), often detailing efficacy, side effects, and resistance mechanisms associated with specific drugs. Additionally, it highlights the importance of the multidisciplinary tumor board and specific diagnostic tools, such as the MCPyV oncoprotein antibody test for MCC surveillance.You can listen and download our episodes for free on more than 10 different platforms:https://linktr.ee/medicine_made_simpleProduced by:https://www.podcaistudio.com/