Advancements in Evidence-Based Research and Nutraceutical Approaches to Managing Long Haul Syndrome with Dr. David Brady

This episode of Conversations for Health features Designs for Health, Inc. and Diagnostic Solutions Laboratory, LLC Chief Medical Officer, Dr. David Brady.  With over 30 years of experience as an integrative practitioner and over 25 years in health sciences academia, Dr. Brady is a licensed naturopathic medical physician & clinical nutritionist, and professor and director emeritus of The Nutrition Institute at the University of Bridgeport.   In our conversation, Dr. Brady explores the rise and implications of long haul syndrome, or PASC, including popular correlation hypotheses, associations and patterns and insights from recent studies.  He details the challenges of major gaps in long haul syndrome clinical care, patient stories, and developing nutraceutical and traditional treatment options that have proven effective, as well as his own case-by-case approach to helping patients manage long haul syndrome effectively as answers continue to be uncovered by researchers and medical professionals.    I'm your host Evelyne Lambrecht, thank you for designing a well world with us.    Key Takeaways:   [1:36] Dr. Brady highlights the defining symptoms of long haul syndrome.  [4:25] The prevalence of long haul syndrome in the U.S., according to a Brooking Institute study. [5:18] Changes in our understanding of long haul syndrome from 2020 to the present.  [8:10] Addressing the major gaps in clinical care regarding long haul syndrome.  [10:33] Hypotheses regarding pathogenesis, mechanisms, and other fundamental long haul syndrome questions.  [13:02] The association between long haul syndrome, immunological cytokine patterns and other metabolomic signatures.  [19:24] Dr. Brady shares the resolution patterns and inconsistencies he has seen in panels.  [21:58] Possible correlations between genetic SNPs and the propensity toward developing long haul syndrome.  [24:43] Insights into the potential correlation between mitochondrial dysfunction and long haul syndrome.  [28:28] Findings from Harvard and Yale long haul molecular and metabolic function studies.  [30:49] Dr. Brady's recommendations for addressing the vasculature aspect of long haul syndrome.  [33:06] Information gained from the microbiota patterns in long haulers.  [35:55] Dr. Brady details the journey of his wife from healthy, fit dancer to long hauler.  [40:30] Evidence based drugs and nutraceuticals that are being used to manage long haul syndrome.  [52:26] Dr. Brady's approach to managing long haul symptoms on a case-by-case basis.  [54:51] Nutraceutical recommendations for approaching long haul syndrome and POTS.  [56:35] Dr. Brady shares his top three favorite supplements, his personal health practices, and what he has changed his mind about in recent years.   Episode Resources:   Dr. David Brady   Presentation: (IHS) Long Covid | Exploring the Latest Science and Pathways Forward   Design for Health Resources:   Designs for Health    Presentation: (CASI 22) Bruce Patterson – Diagnosis, Treatment, and Immunopathogenesis of Chronic Inflammation, including COVID-19 Long-haul syndrome   Presentation: (CASI 22) David Brady – Clinical Round | COVID-19 Long Haul Syndrome   Blog: Specialized Pro-resolving Mediators Novel Mechanisms for Supporting a Healthy Inflammatory Response   Blog: Combination of Geranylgeraniol + Ubiquinol to Support Mitochondrial Function   Blog: Fueling Mitochondria for Illness Recovery   Blog: L-Carnitine for Energy Production and Beyond   Blog: Rhamnan Sulfate to Support the Endothelial Glycocalyx   Blog: How Polyphenols Promote a Healthy Gut Microbiome   Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars and our blog.