AI Can Predict Disease Years Early episode artwork

EPISODE · Dec 14, 2025 · 49 MIN

AI Can Predict Disease Years Early

from AI for Founders with Ryan Estes · host aiforfounders.co

What happens when you build an AI that can spot disease years before symptoms, cut diabetes related complications by 20 percent, and slash healthcare costs, and the market still shrugs. That is the problem my guest today ran straight into.On this episode of AI for Founders, I am talking with Mariano García Valiño, four-time healthcare entrepreneur and CEO of Axenya. Axenya is an AI-powered operating system for corporate health that monitors over one hundred thousand people, runs around ninety-five million clinical inferences a month, and can intelligently route people to care across more than forty conditions, all while pushing costs from two and a half times inflation down toward inflation.If you are a founder building in AI, health tech, or any regulated, incentive-broken industry, this episode is for you. You are going to learn how Mariano redesigned his entire business model so someone actually had a financial reason to pay for prevention, how he thinks about AI as a copilot for doctors instead of a replacement, and how he keeps his sanity and creativity through writing, photography, sports, and reading while running his fourth company.If you want conversations like this distilled into founder ready experiments every week, head to aiforfounders.co and subscribe to the newsletter. https://axenya.comhttps://www.linkedin.com/in/mgarciavalino/__https://aiforfounders.co/ https://ambient.us⁠⁠https://codestory.co⁠https://warmstart.ai ⁠⁠https://kitcaster.com/application ⁠⁠https://ryanestes.info⁠

What happens when you build an AI that can spot disease years before symptoms, cut diabetes related complications by 20 percent, and slash healthcare costs, and the market still shrugs. That is the problem my guest today ran straight into.On this episode of AI for Founders, I am talking with Mariano García Valiño, four-time healthcare entrepreneur and CEO of Axenya. Axenya is an AI-powered operating system for corporate health that monitors over one hundred thousand people, runs around ninety-five million clinical inferences a month, and can intelligently route people to care across more than forty conditions, all while pushing costs from two and a half times inflation down toward inflation.If you are a founder building in AI, health tech, or any regulated, incentive-broken industry, this episode is for you. You are going to learn how Mariano redesigned his entire business model so someone actually had a financial reason to pay for prevention, how he thinks about AI as a copilot for doctors instead of a replacement, and how he keeps his sanity and creativity through writing, photography, sports, and reading while running his fourth company.If you want conversations like this distilled into founder ready experiments every week, head to aiforfounders.co and subscribe to the newsletter. https://axenya.comhttps://www.linkedin.com/in/mgarciavalino/__https://aiforfounders.co/ https://ambient.us⁠⁠https://codestory.co⁠https://warmstart.ai ⁠⁠https://kitcaster.com/application ⁠⁠https://ryanestes.info⁠

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AI Can Predict Disease Years Early

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This episode is 49 minutes long.

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This episode was published on December 14, 2025.

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What happens when you build an AI that can spot disease years before symptoms, cut diabetes related complications by 20 percent, and slash healthcare costs, and the market still shrugs. That is the problem my guest today ran straight into.On this...

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