Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies

Send us Fan MailAlbee Messing, Rachel Battaglia, and Abby Olsen discuss the following recent publication: [01:00]        Alexander disease GFAP R239C mutant shows increased susceptibility to lipoxidation and elicits mitochondrial dysfunction and oxidative stress (Redox Biology, 55:102415, 2022)[14:23]       Questions from email regarding 1) dizziness and 2) risks of brain biopsies. Send your questions and feedback to:  [email protected] support research on Alexander Disease at the University of Wisconsin-Madison's Waisman Center:           https://alexander-disease.waisman.wisc.edu/donate/