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EPISODE · Aug 18, 2026 · 25 MIN

Alexander Shulgin: The Chemist Who Rediscovered MDMA

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Alexander Sasha Shulgin was a Harvard-educated biochemist who synthesized and personally tested more than 200 psychoactive compounds. A strange 1944 placebo experience with sugar-laced orange juice hinted at his lifelong fascination with the mind.This episode follows his path from Dow Chemical, where he invented a blockbuster pesticide, to a backyard laboratory, a federal research license, and the publication that ended his career.Inventing the pesticide sold as Zectran, which funded his research freedomDiscovering DOM and the STP public health crisis in San FranciscoHolding a Schedule I license while consulting for the DEAReintroducing and resynthesizing the forgotten molecule MDMA in 1976Publishing PIHKAL, the 1994 farm raid, and his cognitive liberty stance

Episode metadata supplied by the publisher feed · Published Aug 18, 2026

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