Alpha-1-Antitrypsin Deficiency

A is for alpha-1-antitrypsin! Jody reviews this maybe-not-so-rare genetic disorder that is an important and often overlooked cause of mostly lung and liver disease. References: 1) Stoller, J.K. Clinical manifestations, diagnosis, and natural history of alpha-1-antitrypsin deficiency. UpToDate. https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-natural-history-of-alpha-1-antitrypsin-deficiency 2) Hogarth, D. K. Alpha-1-antitrypsin deficiency. Epocrates. https://www.epocrates.com/online/diseases/1075/alpha-1-antitrypsin-deficiency#highlights-basics 3) Alpha-1-antitrypsin level test. Lippincott Advisor. https://advisor.lww.com/lna/document.do?bid=5&did=1336317&searchTerm=alpha-1-antitrypsin&hits=antitrypsin,alpha 4) Endobronchial Valve Therapy (American Lung Association)