AlphaFold: Grand Challenge to Nobel Prize with John Jumper

from Google DeepMind: The Podcast · host Hannah Fry, John Jumper

Learn more about AlphaFold: https://deepmind.google/science/alphafold/Watch the story behind AlphaFold in The Thinking Game, now available for free: https://youtu.be/d95J8yzvjbQThank you to everyone who made this possible, including but not limited to: Presenter: Professor Hannah FrySeries Producer: Dan HardoonEditor: Rami TzabarCommissioner & Producer: Emma YousifMusic composition: Eleni ShawAudio engineer: Richard CourticeVideo editor: Anthony LeAudio engineer: Perry RogantinVisual identity: Rob AshleyCommissioned by Google DeepMind Please leave us a review on Spotify or Apple Podcasts if you enjoyed this episode. We always want to hear from our audience whether that's in the form of feedback, new idea or a guest recommendation!   Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What this episode covers

Five years ago, AlphaFold 2 solved the protein structure prediction problem, unlocking new avenues of biological research and providing our first major proof point that AI can be a powerful tool to advance science. The profound scientific and societal value of this work was even recognized in 2024 with the Nobel Prize in Chemistry. In this episode, Hannah is joined by John Jumper, one of the most instrumental scientists behind AlphaFold. He shares stories about his Nobel win, the tool's unexpected applications, and the shift in architecture from AlphaFold 2 to the more comprehensive AlphaFold 3.

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AlphaFold: Grand Challenge to Nobel Prize with John Jumper

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This episode was published on November 28, 2025.

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