Anti-tumor role of {gamma}{delta} T cells in expontaneous prostate tumors

In this podcast I will describe a recent manuscript submitted by Liu et al to journal of Immunology 2008; 108:6044 , where {gamma}{delta} T cell knock-out mice were evaluated under situation of expontaneous prostate cancer (crossed with TRAMP mice) and in addition {gamma}{delta} T cells were also used in adoptive therapy settings against established tumors and metastatic disease. The authors show that under the experimental design setting that {gamma}{delta} T cells play a certain role in controlling tumor growth, by reducing the tumor burden and aggressiveness. See you next time