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Are Brain-Computer Interfaces Actually Ready for Humans? episode artwork

EPISODE · Mar 16, 2026 · 1H 13M

Are Brain-Computer Interfaces Actually Ready for Humans?

from This Week in Startups · host Jason Calacanis

This Week In Startups is made possible by: Caldera + Lab - https://CalderaLab.com/TWIST Northwest Registered Agent - https://northwestregisteredagent.com/twist Lemon - https://Lemon.io/twist Today's show: Computers that read your mind? Jets that are all wings? Continuously tracking your body's vital signs to live longer? We've got all that and more on the show today. First, we sat down with the CEO of Paradromics, Matt Angle, to dig into the progress that his brain-computer interface startup has made. Yes, there are more companies working on BCIs than just Neuralink. Paradromics, in particular, is looking for early clinical trial subjects as it works to bring its technology out of the lab and into the market. If you ever wanted to know more about how BCIs work and how long it will be until we can all benefit from the tech, this is the interview for you. Next, we got JetZero CEO Tom O'Leary on the phone to tell us all about his startup's jet. No, it's not competing with Boom, a startup that wants to build a supersonic passenger airliner. Instead, JetZero is building jets that are mostly wing, allowing them to fly with far greater fuel efficiency. Best of all? The future JetZero planes can fit right into normal airports. Finally, we chatted with Nutrisense CEO Dan Zavorotny. While keeping tabs on your glucose levels may not be the sexiest topic in the world, the data that continuous monitoring can bring is incredibly valuable health information. Mix that signal with coaching, and Nutrisense reckons its combination of software, data, and dieticians can really improve health outcomes for its customers. If you needed a break from pure-play AI news, TWiST has you covered! Timestamps: 0:00 Introduction 1:47 Paradromics 3:26 How do BCIs read your mind? 9:58 Lemon - Get 15% off your first 4 weeks of developer time at Lemon.io/twist 19:54 Northwest Registered Agent - Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at northwestregisteredagent.com/twist 27:24 JetZero 29:07 The advantages of more wing 30:13 Caldera Lab - Whether you're starting fresh or upgrading your routine, Caldera Lab makes skincare simple and effective. Head to CalderaLab.com/TWIST and use TWIST at checkout for 20% off your first order. 55:30 Nutrisense Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason's suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com

Episode metadata supplied by the publisher feed · Published Mar 16, 2026

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Are Brain-Computer Interfaces Actually Ready for Humans?

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