Are GLP-1s Safe for Athletes? episode artwork

EPISODE · Jul 16, 2026 · 1H 26M

Are GLP-1s Safe for Athletes?

from The Eat for Endurance Podcast · host Claire Shorenstein, MS RD CSSD with Jenn O'Donnell-Giles, MS RDN

Many athletes are not good candidates for GLP-1s. But for some, these medications can be a useful tool.In episode 141 of The Eat for Endurance Podcast, I'm joined by fellow Sports Dietitian and endurance athlete Jennifer O'Donnell-Giles, MS, RDN for the final installment of my GLP-1 mini-series. Jenn brings 27 years of clinical experience to this conversation, along with a perspective that's evolved a lot over the past few years.Jenn and I discuss:How natural GLP-1 production can decline with ageWhy under-fueling is still the primary issue for many athletesWho should (and shouldn't) consider these medicationsPotential risks of GLP-1 use, including lean body mass loss and GI distressPotential benefits to inflammation, autoimmune conditions, gut health, and moodNutrition and supplement strategies when appetite is lowerDosing and microdosing for therapeutic use, not just weight lossWhy athletes cycle on and off GLP-1s, including around race trainingJenn's own story: early menopause, a cardiovascular family history, and how a short course of GLP-1s changed her health and performanceJenn's biggest takeaway: in the athlete population, a GLP-1 is just one piece of the puzzle, and works best alongside solid nutrition and lifestyle habits. Weight loss can be part of why someone uses one, but there are other potential benefits as well.Whether a GLP-1 is right for an athlete depends on who they are, why they want it, and whether the foundation is already in place. It's not appropriate for everyone, especially anyone with a history of disordered eating or a complicated relationship with food. Tune in for a nuanced, experience-based look at where these medications can genuinely help endurance athletes, and where they can do real harm.Links & ResourcesFollow Jenn on Instagram and visit her website Support my sponsor Tailwind Nutrition: Use code EATFORENDURANCE20 for 20% off your first purchaseJoin my membership, Fuel for Life Crew, for just $39/month (cancel anytime)Check out my free nutrition downloadsSupport the podcast by shopping all my affiliate links and joining my Patreon communityInterested in comprehensive, in-depth 1:1 coaching? Fill out a new client inquiry form (limited spots available)Have a topic you'd like to request? Email me at [email protected] this episode? Please leave a 5-star review and subscribe to help more athletes fuel better!Disclaimer: All information provided is for educational and entertainment purposes only and is not a substitute for individualized medical or nutrition recommendations.Want to get in touch? Send Claire a message!Support the showThanks for listening! Follow me on Instagram and Facebook (@eatforendurance).

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Many athletes are not good candidates for GLP-1s. But for some, these medications can be a useful tool. In episode 141 of The Eat for Endurance Podcast, I'm joined by fellow Sports Dietitian and endurance athlete Jennifer O'Donnell-Giles, MS, RDN for the final installment of my GLP-1 mini-series. Jenn brings 27 years of clinical experience to this conversation, along with a perspective that's evolved a lot over the past few years. Jenn and I discuss: How natural GLP-1 production can decline w...

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Are GLP-1s Safe for Athletes?

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