Are NaV1.8 inhibitors becoming an important new option for acute pain?

This episode reviews four clinically relevant studies: emerging NaV1.8 inhibitors as promising non-opioid therapies for acute pain, a once-weekly oral HIV maintenance regimen demonstrating noninferiority to daily treatment, evidence supporting abbreviated dual antithrombotic therapy after PCI in selected patients with atrial fibrillation, and a meta-analysis showing limited benefit of oral antihistamines for atopic dermatitis. Together, these studies highlight evolving evidence that may influence prescribing practices across multiple specialties