Arizona Cardinals vs San Francisco 49ers Pick 9/27/26 NFL Week 3 Pick Prediction

Arizona Cardinals at San Francisco 49ers by Tony T.The Pick: Arizona has a defensive tackle and nickel back questionable. SF receiver Evans is questionable. 49ers defensive end Bosa is out. Arizona has a significant injury advantage based on Dr Chao ratings of +10.4. This is based on the 49ers players in IR. Jacoby Brissett has lacked efficiency at quarterback with 5.7 yards per pass attempt. Purdy has been efficient with 80.4% completions and 8.8 yards per pass attempt. He has not been sacked. 49ers defense has forced seven turnovers and puts strong pressure on quarterbacks. Play San Francisco -8.

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Arizona Cardinals vs San Francisco 49ers Pick 9/27/26 NFL Week 3 Pick Prediction

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