EPISODE · Dec 27, 2025 · 19 MIN
Atopic Keratoconjunctivitis (AKC)
from OrphaChat — a Rare Disease Podcast · host RCH
In this episode, we explore Atopic Keratoconjunctivitis (AKC), a severe, chronic inflammatory eye disease that primarily affects adults between 20 and 50 years old with a history of atopic dermatitis or asthma. We discuss the condition's distinct clinical features—such as intense itching, eczematous eyelids, and lower tarsal conjunctival involvement—and how to differentiate it from the pediatric-onset Vernal Keratoconjunctivitis. Finally, we review management strategies ranging from topical antihistamines and corticosteroids to steroid-sparing immunomodulators like tacrolimus and cyclosporine, as well as surgical interventions for preventing permanent vision loss from corneal scarring.
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Atopic Keratoconjunctivitis (AKC)
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