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Auvelity: A Novel Antidepressant episode artwork

Feb 2, 2026 10 min

Auvelity: A Novel Antidepressant

from Knowledgeable Provider Hosted by Jody Marks, MSN, AGACNP-BC, FNP-BC

It's a new medicine made of old medicines! Jody reviews the mechanism of this new (?) option for treatment of major depressive disorder in adults. References: 1) Auvelity Package Insert 2) Auvelity Review Article (Annals of Medicine & Surgery) 3) Auvelity Overview (OpenEvidence) 4) Physiology of NMDA Receptor (PubMed) 5) Pharmacology of Sigma-1 Receptor (PubMed) 6) Mucinex DM Label Information

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Auvelity: A Novel Antidepressant

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