Banking on New Eosinophilic Esophagitis (EoE) Treatments

In today's episode we discuss an immune-mediated disease, eosinophilic esophagitis, or EoE. We review the symptoms, risks, and damage this disease can cause. We also get into what happens inside the body during and what's being done in both standard medicine and clinical research to try to end EoE.References:[1] Muir, A., & Falk, G. W. (2021). Eosinophilic esophagitis: a review. Jama, 326(13), 1310-1318. https://pmc.ncbi.nlm.nih.gov/articles/PMC9045493/[2] Nurko, S., & Furuta, G. T. (2006). Eosinophilic esophagitis. GI Motility online. https://www.nature.com/gimo/contents/pt1/full/gimo49.html[3] Rochman, Y., Kotliar, M., Ben-Baruch Morgenstern, N., Barski, A., Wen, T., & Rothenberg, M. E. (2023). TSLP shapes the pathogenic responses of memory CD4+ T cells in eosinophilic esophagitis. Science signaling, 16(802). https://pmc.ncbi.nlm.nih.gov/articles/PMC10602003/[4] Dellon, E. S., Gonsalves, N., Hirano, I., Furuta, G. T., Liacouras, C. A., & Katzka, D. A. (2013). ACG clinical guideline: evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE). American Journal of Gastroenterology, 108(5), 679-692. https://journals.lww.com/ajg/fulltext/2013/05000/ACG_Clinical_Guideline__Evidenced_Based_Approach.10.aspx?context=FeaturedArticles&collectionId=2[5] He, R., & Geha, R. S. (2010). Thymic stromal lymphopoietin. Annals of the New York Academy of Sciences, 1183(1), 13-24. https://pmc.ncbi.nlm.nih.gov/articles/PMC2895428/Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInTiktokYoutubeFor more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.comThank you for listening!