BCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces episode artwork

EPISODE · Oct 3, 2025 · 36 MIN

BCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces

from State of Medtech · host State of Medtech

Brain–computer interfaces are no longer science fiction. Matt Angle, Founder and CEO of Paradromics, joins Omar Khateeb to discuss how his company is building the world’s highest data–rate BCI.From his neuroscience roots at Stanford to raising capital in Austin, Matt shares how Paradromics is preparing for first-in-human trials in ALS patients, why data rate is the real bottleneck, how their platform stacks up against Neuralink, and why investors like Saudi Arabia’s NEOM are betting on this future.This episode covers the technology, the business, and the ethics behind connecting brains and machines.Episode Breakdown: 00:00 – What is a Brain-Computer Interface (BCI)? 01:02 – Introducing Paradromics and CEO Matt Angle 02:01 – Matt’s background: neuroscience at Heidelberg & Stanford 03:25 – Early BCI research and limitations of older systems 04:46 – Why Paradromics moved to Austin, Texas 06:28 – How Paradromics technology works: recording at the neuron level 09:50 – Surgical process for BCI implantation 11:08 – Paradromics vs. Neuralink: 10x higher data rates 11:53 – First application: restoring speech for ALS & paralysis patients 13:43 – Potential of BCIs in mental health and mood tracking 15:30 – Psychiatry’s challenge: lack of data vs. future of “brain work” 19:06 – Strategic partnership with Saudi fund NEOM 21:27 – Paradromics’ 3–5 year roadmap: hardware + applications 24:10 – Why BCIs could disrupt pharmaceuticals and drug dosing 26:09 – M&A potential in BCI: role of Medtronic, Abbott, Boston Scientific 29:03 – Why medical devices have staying power vs. drugs 30:12 – Market size: $400B+ opportunity for BCIs 32:16 – Cybersecurity and neural data protection 33:49 – The FDA BCI Collaborative Community 34:42 – Upcoming BCI Society meeting in Banff, Canada 35:11 – Closing thoughts & where to find Paradromics onlineAre you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GrowMyMedtech.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to book time for a free analysis.Subscribe to our Youtube Channel⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCGpL_rGt1LQJwinMq_K7gfg⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to our LinkedIn Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.stateofmedtechpodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow The State of MedTech onLinkedIn ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/company/thestateofmedtech⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/stateofmedtech/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@stateofmedtech⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠X ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/StateofMedTech⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/stateofmedtech/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Omar M. Khateeb onLinkedIn ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/okhateeb/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/omar.m.khateeb/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@omarkhateebofficial⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠X ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/OmarMKhateeb⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/OmarMKhateeb/⁠⁠⁠⁠⁠⁠⁠This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions#Medtech #AFib #HealthcareInnovation #Cardiology #AIinHealthcare #StateofMedTech #MedicalDevices

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BCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces

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