Best Practices and Potential Pitfalls Enriching Clinical Trials with PROs

Patient-reported outcomes (PROs) are increasingly recognized by regulators, clinicians, and patients as valuable tools to collect patient-centered data. This podcast features a panel discussion from the 2025 Chief Medical Officer Summit 360° with biotech CMOs about how to incorporate PROs into clinical trials in ways that improve probabilities of success while avoiding common mistakes. Specifically, the panelists address:How PROs provide evidence on the effect of interventions on patient symptoms and quality of life, but by the nature of being subjective, they are prone to bias The growth of electronic health technologies provides unprecedented opportunities to systematically collect PROsDisadvantages of electronic methods include technical difficulties, cost, longer start-up time, and “digital divide” between patientsTo learn more about the Chief Medical Officer Summit 360°, please visit CMO360.org.