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EPISODE · Aug 25, 2025 · 15 MIN

Best supplements for Sciatica Pain

from Functional Rehab Podcast · host Dr. Ashley Mak, PT, DPT, CSCS

In this episode, Dr. Ashley Mak discusses the role of supplements in managing sciatica and nerve pain. He emphasizes the importance of understanding the causes of sciatica and highlights the most researched supplements, including alpha lipoic acid, B vitamins, and palmitolethylamide. The conversation also covers supplements with mixed evidence, such as turmeric and MSM, and provides guidelines for safely using supplements. Dr. Mak concludes by stressing the importance of consulting healthcare professionals before starting any new supplement regimen. Referenced Research Articles 1. Alpha-Lipoic Acid (ALA) Systematic Review and Meta-Analysis: https://www.researchgate.net/publication/375279477_Systematic_Review_and_Meta-Analysis_Medicine_R_Effectiveness_of_alpha-lipoic_acid_in_patients_with_neuropathic_pain_associated_with_type_I_and_type_II_diabetes_mellitus_A_systematic_review_and_meta-an Review Article: https://pmc.ncbi.nlm.nih.gov/articles/PMC9774895/ 2. B Vitamins (especially B12) Systematic Review: https://www.mdpi.com/2072-6643/12/8/2221 Systematic Review and Meta-Analysis: https://pubmed.ncbi.nlm.nih.gov/33619867/ 3. Palmitoylethanolamide (PEA) Review of Clinical Applications: https://www.dovepress.com/palmitoylethanolamide-in-the-treatment-of-pain-and-its-clinical-applic-peer-reviewed-fulltext-article-DDDT Meta-Analysis: https://pubmed.ncbi.nlm.nih.gov/39798151/ 4. Other Supplements Turmeric (Curcumin): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125634/ MSM (Methylsulfonylmethane): https://www.researchgate.net/publication/7458879_Efficacy_of_methylsulfonylmethane_MSM_in_osteoarthritis_pain_of_the_knee_A_pilot_clinical_trial Arnica: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539394/ Check out our favorite products! (affiliate page): https://ifixyoursciatica.gymleadmachine.co/favorite_products Did you know that our YouTube channel has a growing number of videos including this podcast? Give us a follow here- https://youtube.com/@fixyoursciatica?si=1svrz6M7RsnFaswN Are you looking for a more affordable way to manage your pain? Check out the patient advocate program here: ptpatientadvocate.com Here’s the self cheat sheet for symptom management: https://ifixyoursciatica.gymleadmachine.co/self-treatment-cheat-sheet-8707 Book a free strategy call: https://msgsndr.com/widget/appointment/ifixyoursciatica/strategy-call Advertising Inquiries: https://redcircle.com/brands Privacy & Opt-Out: https://redcircle.com/privacy

Episode metadata supplied by the publisher feed · Published Aug 25, 2025

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Best supplements for Sciatica Pain

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