Betaine in early onset MTHFR Deficiency

Professor Manuel Schiff joins podcast host James Nurse to discuss a recent study looking at the successful use of Betaine in the management of early-onset MTHFR deficiency. Influence of early identification and therapy on long-term outcomes in early-onset MTHFR deficiency Mathilde Yverneau, et al (2022) https://doi.org/10.1002/jimd.12504 Interested listeners may also want to read: Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency Martina Huemer, et al (2016) https://doi.org/10.1007/s10545-016-9991-4