Beyond Triheptanoin: Elamipretide and Cardiolipin Remodelling in TFP Deficiency episode artwork

EPISODE · Mar 3, 2026 · 20 MIN

Beyond Triheptanoin: Elamipretide and Cardiolipin Remodelling in TFP Deficiency

from JIMD Podcasts · host Journal of Inherited Metabolic Disease

We talk with Eduardo Vieira Neto about elamipretide in mitochondrial trifunctional protein deficiency and the emerging role of cardiolipin remodelling beyond classic fatty-acid oxidation. Could this offer an add-on approach for complications that triheptanoin doesn’t fully address? Elamipretide Improves Mitochondrial Function in Mitochondrial Trifunctional Protein-Deficient Mice and Human Fibroblasts Eduardo Vieira Neto, et al https://doi.org/10.1002/jimd.70132

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Beyond Triheptanoin: Elamipretide and Cardiolipin Remodelling in TFP Deficiency

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