Big Beautiful Bill Breakdown, Orphan Cures Win, and What’s Next | Making Medicine Podcast Relaunch

John Stanford kicks off the official relaunch of the Making Medicine Podcast with a deep dive into the "one big beautiful bill" that’s shaking up Washington. From major tax cuts to game-changing reforms like the Orphan Cures Act, this episode covers what’s in—and what’s not—in the sweeping legislation. What’s the real impact on biotech innovation, Medicaid, PBMs, and future drug pricing? John breaks it all down while teasing what’s ahead in upcoming episodes, including Trump’s proposed pharma tariffs and the evolving role of the FDA.Do you think the Orphan Cures Act goes far enough?How will these tax and policy shifts impact innovation in rare disease and biotech?📱If you're new to the Making Medicine Podcast, we're happy you're here! Follow us for more:https://x.com/MakingMedPodhttps://www.instagram.com/makingmedicinepod/https://www.linkedin.com/showcase/making-medicine-podcast/about/?viewAsMember=trueTimestamps:0:00 Welcome to Making Medicine0:18 Podcast relaunch and weekly content1:00 One big beautiful bill becomes law1:38 Tax cuts, deficit concerns, and social program impacts2:55 How the bill affects biotech and venture capital3:26 Orphan Cures Act and rare disease investment4:20 Inflation Reduction Act reforms not included4:40 PBM cuts left out of the bill5:20 Victory on Most Favored Nations policy6:24 What “pay for” means in DC speak6:59 Industry spared from being a “pay for”7:03 What’s coming next: tariffs, NIH cuts, FDA changes7:45 Subscribe and stay updated