Bills dream start to season hits major roadblock vs. Titans | What's going on with this defense?

Matt Parrino and Ryan Talbot react to the Bills' 42-16 loss to the Titans on Tuesday Night Football. Without Tre'Davious White and Matt Milano, the defense struggles to contain the Titans offense, which got to work on several short fields throughout the game. The Bills offense made its mark on big plays through the first four weeks, but without John Brown in the lineup those plays never materialized. Did the Covid-19-induced haze to the week impact the game? The guys react and break down what happened in Nashville. "Shout!" A Buffalo Bills football podcast is available on Apple, Spotify, Google, Stitcher, Acast and wherever you listen to podcasts. The show is brought to you by Tops Friendly Markets (https://www.topsmarkets.com/). Follow @MattParrino (https://twitter.com/MattParrino) and @RyanTalbotBills (https://twitter.com/RyanTalbotBills) on Twitter Find our Bills coverage wherever you like to consume social media: Instagram: https://www.instagram.com/buffalobillsnyup Facebook: https://www.facebook.com/buffalobillsnyup Twitter: https://twitter.com/billsupdates For all your Bills coverage head to https://www.syracuse.com/buffalo-bills/ See acast.com/privacy for privacy and opt-out information. Learn more about your ad choices. Visit megaphone.fm/adchoices