Brad Schoenfeld: The Science Of Building Muscle & Maximising Strength episode artwork

EPISODE · Oct 28, 2025 · 52 MIN

Brad Schoenfeld: The Science Of Building Muscle & Maximising Strength

from Hack You · host Vadim Fedotov, Mike Thurston

Brad Schoenfeld has published over 200 peer-reviewed studies on muscle hypertrophy, and his research reveals why most people are training with far less volume than optimal, but adding more sets isn't always the answer.After analysing decades of resistance training data, Brad discovered that the relationship between volume and muscle growth follows a dose-response curve with a point of diminishing returns that varies dramatically between individuals. While some respond to 6 sets per muscle group per week, others need 20+ sets to maximise growth, and the difference comes down to factors most trainers never consider when programming.Tune in to find out your optimal training volume, why the "10 sets per muscle group" recommendation is oversimplified, and the specific markers that tell you when you've crossed from productive to junk volume.00:00 Introduction04:11 Understanding optimal training volume and individual variability09:01 Effective rep ranges and importance of training to near failure13:09 Mixing rep ranges for hypertrophy and the science behind it15:11 Myths debunked by research including rest times and nutrient timing18:23 Clarifying protein timing and muscle protein synthesis windows23:00 Does lifting tempo matter and how to think about it27:23 Eccentric vs concentric movement and site-specific muscle growth30:15 Advanced techniques like eccentric overload and when to use them31:43 Designing a hypertrophy programme with just three sessions a week36:07 The hype and nuance behind training in the lengthened position40:28 Longevity benefits of resistance training beyond aesthetics45:06 Muscle memory explained from neurological and cellular angles47:09 How to adjust training for older individuals49:07 Signs you're under-recovered and when to back off50:49 The future of hypertrophy training through genetic profilingDISCLAIMERNothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.Hack You Media→ Instagram: https://www.instagram.com/hackyoumedia/→ TikTok: https://www.tiktok.com/@hack.you.media?lang=en→ More from Hack You: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5» Follow Vadim«Instagram: https://www.instagram.com/vadim_bioniq/?hl=enBioniq: https://www.bioniq.com/» Follow Mike«YouTube: youtube.com/MikeThurstonInstagram: https://www.instagram.com/mikethurston/?hl=enFirst Things THRST: youtube.com/FirstThingsThrst» Follow Brad«Instagram: https://www.instagram.com/bradschoenfeldphd/Website: https://linktr.ee/bradschoenfeld

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