Brad Younggren: Filtering Out Aging episode artwork

EPISODE · Jun 10, 2026 · 42 MIN

Brad Younggren: Filtering Out Aging

from We're not getting any younger... yet. · host The Buck Institute

What if removing and replacing part of your blood could turn back some of the measurable signs of aging? Brianna Stubbs talks with Dr. Brad Younggren — emergency physician, former Army doctor, and CEO of Circulate Health — about therapeutic plasma exchange (TPE). They cover how the procedure works, what the blinded Circulate trial found (including an average 2.6-year reduction in biological age over three months), TPE's unique potential to clear microplastics from the bloodstream, and the broader impact of our environment—the exposome—on human healthspan.Brad Younggren, MD, is CEO and co-founder of Circulate Health, a company dedicated to improving human healthspan. A former U.S. Army physician, Dr. Younggren served as a combat physician in Iraq and was awarded a Bronze Star and Combat Medical Badge. An emergency medicine specialist and seasoned healthcare executive, Younggren has led teams at the cutting edge of medicine for decades. Most recently, he was President and Chief Medical Officer at 98point6, where he led the development and launch of AI-powered primary care solutions. He previously served as Chief Medical Officer at Cue Health, Shift Labs, and Mobisante. At Circulate, Younggren leads an expert team of clinicians and scientists working to harness the potential of therapeutic plasma exchange to advance health and longevity.Support the show

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What if removing and replacing part of your blood could turn back some of the measurable signs of aging? Brianna Stubbs talks with Dr. Brad Younggren — emergency physician, former Army doctor, and CEO of Circulate Health — about therapeutic plasma exchange (TPE). They cover how the procedure works, what the blinded Circulate trial found (including an average 2.6-year reduction in biological age over three months), TPE's unique potential to clear microplastics from the bloodstream, and the bro...

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Brad Younggren: Filtering Out Aging

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