Brass Lights in the Blind Spot

What this episode covers

This release contains only the music track from Base by Base Episode 350. Song title: Brass Lights in the Blind SpotOriginal Base by Base episode: 350: OPA1 A8S in Rhesus Macaques Models Autosomal Dominant Optic Atrophy Article metadata:Article title: Rhesus macaques with an OPA1 mutation demonstrate features of autosomal dominant optic atrophyJournal: PNASDOI: 10.1073/pnas.2509165123Reference: Jaggers TN et al., Rhesus macaques with an OPA1 mutation demonstrate features of autosomal dominant optic atrophy. PNAS. 2026;123:e2509165123. https://doi.org/10.1073/pnas.2509165123 Lyrics:Verse 1Under bright screens in a midnight labA single letter turns the map to grayQuiet wires from the eye to the brainStart losing spark along the way Pre-ChorusIn the smallest shift, a signal bendsPower slips where it should stayBut we can trace the break in the lineAnd name what fades ChorusOh, bring the brass lights back to the nerveLet the rhythm carry what it’s worthWhen the engines stutter, we learn the tuneAnd we’ll build them stronger soonSo raise that beat for the cells that serveWe’re not done—bring the brass lights back to the nerve Verse 2In the fovea’s focus, a fragile threadGanglion voices thin and dimMitochondria miss the road they knewCrowd less, twist strange, run thin BridgeIf dynamics fail, the cables frayAxon, myelin, torn by timeBut this mirror in living eyesGives us a trial run before the climbWe’ll aim protection where the power goesAnd rewrite the fault in the code Final ChorusOh, bring the brass lights back to the nerveLet the rhythm carry what it’s worthWe saw the loss, we saw the proofNow we chase the rescue routeSo raise that beat for the cells that serveWe’re not done—bring the brass lights back to the nerve

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