Breakthrough: The stories behind Life-Changing Therapies | Dr. William Pao former CDO of Pfizer episode artwork

EPISODE · Jun 11, 2025 · 1H 17M

Breakthrough: The stories behind Life-Changing Therapies | Dr. William Pao former CDO of Pfizer

from Nucleate Podcast · host Nucleate

Follow us at https://signal.nucleate.xyz0:03:41 - Dr. Pao discusses losing his father to colon cancer at age 13, which motivated his career in medicine0:05:30 - Describes his early academic training, including his PhD work on Gamma Delta T cells0:09:54 - Begins discussing the EGFR mutation discovery in lung cancer research 0:13:16 - Shares the story of being "scooped" by other researchers when publishing his EGFR mutation findings0:32:44 - Starts discussing his book "Breakthrough: The Quest for Life-Changing Medicines"0:42:35 - Tells the serendipitous story of Tylenol's discovery0:58:38 - Begins discussing entrepreneurship and decision-making in drug development1:04:29 - Talks about starting his own company, Revelio Therapeutics1:11:28 - Discusses future trends in medical research and potential breakthrough areas1:15:52 - Offers final advice about resilience for aspiring entrepreneurs and scientists These timestamps highlight key moments in the conversation about Dr. Pao's career, research, book, and insights into medical innovation.

Episode metadata supplied by the publisher feed · Published Jun 11, 2025

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Dr. William Pao joins the Nucleate Podcast to share his inspiring journey from losing his father to cancer to leading groundbreaking cancer research and founding Revelio Therapeutics. He discusses the discovery of EGFR mutations, the stories behind his book Breakthrough, and what it takes to bring life-changing drugs to patients. Tune in for insights on biotech innovation, scientific resilience, and the future of medicine and check out Breakthrough on Amazon or a bookstore near you.

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Breakthrough: The stories behind Life-Changing Therapies | Dr. William Pao former CDO of Pfizer

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