Breath Work and Brain Health episode artwork

EPISODE · Nov 22, 2025 · 12 MIN

Breath Work and Brain Health

from The Longevity Podcast: Optimizing HealthSpan & MindSpan · host Dung Trinh

Send us Fan MailWe explore how breathing mechanics and brain circuits work together to regulate pH, emotion and attention, and why CO2 is the hidden driver of ventilation. We share evidence that slow, deliberate breathing reduces fear responses and offer simple drills to change your baseline state.• CO2 and pH as the primary targets of ventilation• Diaphragm mechanics and alveoli surface area• Brainstem rhythm generators and CO2 sensors• The physiological sigh as alveolar maintenance• Lessons from early ventilators on periodic super breaths• Pathways from breath to brain: olfaction, vagus, chemistry, volition• Evidence that slow breathing reduces fear circuitry activity• Practical box breathing protocol and use cases• Magnesium L threonate and support for plasticity and cognitionTry five minutes of box breathing: five seconds in, five hold, five out, five holdThis podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice. Never miss an episode—subscribe on your favorite podcast app!

Send us Fan Mail We explore how breathing mechanics and brain circuits work together to regulate pH, emotion and attention, and why CO2 is the hidden driver of ventilation. We share evidence that slow, deliberate breathing reduces fear responses and offer simple drills to change your baseline state. • CO2 and pH as the primary targets of ventilation • Diaphragm mechanics and alveoli surface area • Brainstem rhythm generators and CO2 sensors • The physiological sigh as alveolar maintenance • ...

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Breath Work and Brain Health

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This episode is 12 minutes long.

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This episode was published on November 22, 2025.

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Send us Fan MailWe explore how breathing mechanics and brain circuits work together to regulate pH, emotion and attention, and why CO2 is the hidden driver of ventilation. We share evidence that slow, deliberate breathing reduces fear responses and...

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