Brody's Human Pharmacology: Mechanism-Based Therapeutics

An extensive overview of human pharmacology, examining the mechanisms of drug action, pharmacokinetics, and clinical applications across multiple systems and disorders. They begin by introducing key pharmacological concepts like drug nomenclature (chemical, generic, and trade names) and the quantitative relationship between drug concentration and physiological response at the receptor level. A significant portion focuses on the autonomic and central nervous systems, detailing receptor families (e.g., cholinergic, adrenergic, GABAergic), neurotransmission, and the use of agonists and antagonists to treat conditions like hypertension, depression, anxiety, Parkinson disease, and Alzheimer disease. Furthermore, the text explores drug development, including the lengthy and complex process of bringing therapeutics to market, and specific drug classes such as antiseizure medications, analgesics (opioids and NSAIDs), immunosuppressives, and agents for conditions like gout and alcohol use disorder, often including details on adverse effects and pharmacokinetics.You can listen and download our episodes for free on more than 10 different platforms:https://linktr.ee/pharmacy_simpleProduced by:https://www.podcaistudio.com/