Calculating Kidney Function for Patients of All Races

Calculating an accurate renal function in patients is crucial to ensure the right dose gets to the right patient. Previous equations to estimate glomerular filtration rate depended on a race variable. However, recent data suggests this underestimates the risk of chronic kidney disease in black patients. In this episode, host Geoff Wall discusses different methods to calculate kidney function and the relationship between mortality, kidney failure, and race The GameChanger The newly proposed eGFRcr-cys equation was the most accurate in estimating the relationship of GFR to poor outcomes regardless of race. However, even with this equation, black patients were almost uniformly found to have poorer outcomes than non-black patients  Show Segments 00:00 – Introductions 01:30 – Kidney Function and Kidney Disease 03:00 – Estimating Kidney Function Based on Race 07:44 – Cystatin C vs Creatinine Clearance  09:57 – Association of Estimated GFR Calculated Using Race-Free Equations with Kidney Failure and Mortality by Black vs Non-Black Race   16:11 – The GameChanger  19:25 – Connecting to Practice 21:16 – Closing Remarks   HostGeoff Wall, PharmD, BCPS, FCCP, CGP Professor of Pharmacy Practice, Drake University Internal Medicine/Critical Care, UnityPoint Health  References and Resources Association of Estimated GFR Calculated Using Race-Free Equations with Kidney Failure and Mortality by Black vs Non-Black Race Redeem your CPE or CME here CPE (Pharmacist)  CME (Physician)   Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode) Pharmacists: Get a membership Prescribers: Get a membership   CE InformationLearning Objectives Upon successful completion of this knowledge-based activity, participants should be able to: 1. Describe the equation that best estimates risk of poor outcomes in patients with chronic kidney disease regardless of race 2. List barriers to implementing cystatin-C testing in clinic laboratories  0.05 CEU/0.5 Hr UAN: 0107-0000-22-280-H01-P Initial release date: 08/01/2022 Expiration date: 08/01/2023 Additional CPE and CME details can be found here. Follow CEimpact on Social Media:LinkedInInstagram