Can blood tests reliably guide Alzheimer’s diagnosis in patients with cognitive decline?

New guidelines from the 2025 Alzheimer’s Association International Conference support using high-performing blood tests to help diagnose Alzheimer’s in memory care patients, offering a less invasive option than spinal taps or PET scans. A NEJM trial found the smaller NTCU380mini IUD nearly as effective as the standard TCU380A, with fewer side effects and better tolerability. Lastly, a large study showed that adults with diabetes who exercised—even only on weekends—had significantly lower mortality, supporting flexible activity patterns.