EPISODE · May 28, 2026 · 49 MIN
Can Exercising With Oxygen Help Heal Your Autoimmune Disease? — with Brad Pitzele of One Thousand Roads
from The Biohacking Blondes · host Molly Segal and Alexandra Cochrane
On today’s episode we interviewed Brad Pitzele, founder of One Thousand Roads. Brad shares how a lifelong struggle with autoimmune symptoms, psoriatic arthritis, Lyme disease, Bartonella, brain fog, fatigue, and chronic inflammation led him to build his own Exercise With Oxygen Therapy system. That personal journey eventually grew into a wellness technology company focused on oxygen therapy, mitochondrial health, red and near-infrared light, circulation, and recovery. Brad named his company One Thousand Roads after trying countless diets, healing protocols, supplements, doctors, and healers. The road that finally changed his health was oxygen therapy.Brad also explains how hidden infections can sometimes be an overlooked driver behind autoimmune conditions. He shares why standard testing and treatment may miss the bigger picture, and how therapies like EWOT may help support oxygen delivery, cellular energy, and resilience. This conversation is especially powerful for anyone who has been told they are stuck with an autoimmune diagnosis for life, but still feels there may be a deeper root cause at play.Brad’s Simple Protocol1. EWOT: 15 minutes (treadmill, bike, elliptical, walking, etc)2. Red Light Therapy: 7–10 minutes after EWOT3. Repeat: 3–5 times per weekSave Up to $500 on an EWOT (Exercise with Oxygen Therapy) system for your home with our link below:https://www.onethousandroads.com/BiohackingBlondesTop 5 Takeaways:1. Autoimmune symptoms may have deeper root causesBrad’s story is a reminder that psoriasis, psoriatic arthritis, Raynaud’s, fatigue, brain fog, and other “mystery” symptoms may sometimes be connected to hidden infections like Lyme disease or Bartonella. If you are struggling with autoimmune issues and not getting answers, it may be worth looking deeper.2. Lyme and co-infections can be missed by standard testingBrad explains how Lyme can become a “do-it-yourself illness” for many people because conventional testing may miss cases, symptoms can look like other conditions, and insurance coverage for advanced testing and treatment can be limited.3. EWOT is designed to flood the body with oxygen during exerciseExercise With Oxygen Therapy, or EWOT, involves exercising while breathing concentrated oxygen through a mask. The goal is to use the natural effects of exercise, like increased heart rate, deeper breathing, and better circulation, to drive more oxygen into the tissues.4. Oxygen therapy may support energy, brain fog, and mitochondrial functionBrad noticed that exercise felt easier almost immediately, and over time he experienced improvements in brain fog, energy, and overall function. For people dealing with chronic inflammation or fatigue, oxygen delivery and mitochondrial support may be a key piece of the puzzle.5. Stacking EWOT with red and near-infrared light may enhance resultsBrad explains how EWOT helps deliver oxygen, while red and near-infrared light may support blood flow and help mitochondria use oxygen more efficiently. Together, these tools may offer a powerful cellular health strategy for recovery, inflammation, and performance.Links:Website:https://www.onethousandroads.com/BiohackingBlondesInstagram: https://www.instagram.com/onethousandroadshq/YouTube: https://www.youtube.com/@OneThousandRoadsHQLearn more about EWOT: https://www.onethousandroads.com/pages/exercise-with-oxygen-therapy
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Can Exercising With Oxygen Help Heal Your Autoimmune Disease? — with Brad Pitzele of One Thousand Roads
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