Can Louisville Shock Ole Miss? | Louisville Football News

Louisville’s season opener against No. 9 Ole Miss is a high-stakes showdown with playoff implications — and history says they’re not supposed to win. The Cardinals are winless in seven previous Week One games against ranked teams, often by blowout margins. But under Coach Jeff Brohm, they’ve flipped the script, beating top-15 squads including Notre Dame, Clemson, and even second-ranked Miami. Can Brohm lead Louisville to an upset that catapults them into the playoff conversation? This game isn’t just about pride — it’s about rewriting their season’s narrative on day one. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/4d11f922c55fee61