Can Ozempic, Zepbound or Mounjaro Truly Transform Rheumatoid and Psoriatic Arthritis?

Can Ozempic, Mounjaro, Zepbound and Wegovy calm inflammation — not just melt away weight? In this episode of Thriving with Arthritis, Dr. Diana Girnita, board-certified rheumatologist and PhD in immunology, sits down with Dr. Vishnuteja Devalla to unpack the fast-growing science of GLP-1 medications in rheumatoid arthritis and psoriatic arthritis.They break down how GLP-1 drugs actually work, why the same receptor lives on your immune cells, and what the latest evidence really shows for autoimmune disease — separating real science from the headlines and hype.In this episode:What GLP-1 medications are and how they work (Ozempic, Wegovy, Mounjaro, Zepbound explained)The key difference between semaglutide and tirzepatide — and why GIP matters for weight lossHow GLP-1 receptors on macrophages, neutrophils, and T cells calm inflammationThe surprising drop in TNF-alpha, IL-1, IL-6 — the exact targets of our biologicsWhat the UCLA study and PASI data reveal for RA and psoriatic arthritisWhy obesity fuels inflammation and drives worse treatment responseWill GLP-1s ever replace methotrexate or biologics? (The honest answer)Microdosing GLP-1s for inflammation — lower cost, fewer side effectsThe compounded-medication warning every patient needs to hearHow to safely reduce medication when you start feeling betterWhere GLP-1 therapy is heading in the next 5 years⚠️ This podcast is for educational purposes only and is not medical advice. Always talk with your own rheumatologist before starting, stopping, or changing any medication.Support the showMore info about Dr. Diana Girnita, MD PhDWebsite: https://rheumatologistoncall.com/Email: [email protected]: https://www.youtube.com/@rheumatologistoncallLinkedIn: https://www.linkedin.com/in/diana-girnita-md-phd-07b57810/Instagram: https://www.instagram.com/rheumatologistoncall/Facebook Page: https://www.facebook.com/RheumatologistOncall/Facebook Group: https://www.facebook.com/groups/3685130571554200