Can starting a medication abortion before confirming an intrauterine pregnancy offer a safe, effective alternative to waiting?

NEJM reports on the safety of very early medication abortion, showing that initiating abortion medication before ultrasound confirmation is as effective and safe as the standard approach, reducing barriers in restricted settings. Another study highlighted the long-term survival impact of combining dabrafenib and trametinib for resected stage III melanoma patients with *BRAF* V600 mutations, noting a potential benefit for specific genetic profiles despite statistical limitations. Lastly, a Science study revealed that reduced sugar intake during the first thousand days of life significantly lowers the risk of diabetes and hypertension, emphasizing early intervention as a lifelong health measure.