Cancer's power harnessed — lymphoma mutations supercharge T cells episode artwork

EPISODE · Feb 7, 2024 · 35 MIN

Cancer's power harnessed — lymphoma mutations supercharge T cells

from Nature Podcast

In this episode:0:46 Borrowing tricks from cancer could help improve immunotherapyT cell based immunotherapies have revolutionised the treatment of certain types of cancer. However these therapies — which involved taking someone’s own T cells and reprogramming them to kill cancer cells — have struggled to treat solid tumours, which put up multiple defences. To overcome these, a team has taken mutations found in cancer cells that help them thrive and put them into therapeutic T cells. Their results show these powered-up cells are more efficient at targeting solid tumours, but don’t turn cancerous themselves.Research article: Garcia et al.11:39 Research HighlightsHow researchers solved a submerged-sprinkler problem named after Richard Feynman, and what climate change is doing to high-altitude environmental records in Switzerland.Research Highlight: The mystery of Feynman’s sprinkler is solved at lastResearch Highlight: A glacier’s ‘memory’ is fading because of climate change14:28 What might the car batteries of the future look like?As electric cars become ever more popular around the world, manufacturers are looking to improve the batteries that power them. While conventional lithium-ion batteries have dominated the electric vehicle market for decades, researchers are developing alternatives that have better performance and safety — we run though some of these options and discuss their pros and cons.News Feature: The new car batteries that could power the electric vehicle revolution25:32 Briefing ChatHow a baby’s-eye view of the world helps an AI learn language, and how the recovery of sea otter populations in California slowed rates of coastal erosion.Nature News:This AI learnt language by seeing the world through a baby’s eyesNews: How do otters protect salt marshes from erosion? ShellfishlySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

In this episode:0:46 Borrowing tricks from cancer could help improve immunotherapyT cell based immunotherapies have revolutionised the treatment of certain types of cancer. However these therapies — which involved taking someone’s own T cells and reprogramming them to kill cancer cells — have struggled to treat solid tumours, which put up multiple defences. To overcome these, a team has taken mutations found in cancer cells that help them thrive and put them into therapeutic T cells. Their results show these powered-up cells are more efficient at targeting solid tumours, but don’t turn cancerous themselves.Research article: Garcia et al.11:39 Research HighlightsHow researchers solved a submerged-sprinkler problem named after Richard Feynman, and what climate change is doing to high-altitude environmental records in Switzerland.Research Highlight: The mystery of Feynman’s sprinkler is solved at lastResearch Highlight: A glacier’s ‘memory’ is fading because of climate change14:28 What might the car batteries of the future look like?As electric cars become ever more popular around the world, manufacturers are looking to improve the batteries that power them. While conventional lithium-ion batteries have dominated the electric vehicle market for decades, researchers are developing alternatives that have better performance and safety — we run though some of these options and discuss their pros and cons.News Feature: The new car batteries that could power the electric vehicle revolution25:32 Briefing ChatHow a baby’s-eye view of the world helps an AI learn language, and how the recovery of sea otter populations in California slowed rates of coastal erosion.Nature News:This AI learnt language by seeing the world through a baby’s eyesNews: How do otters protect salt marshes from erosion? ShellfishlySubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

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Cancer's power harnessed — lymphoma mutations supercharge T cells

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This episode is 35 minutes long.

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This episode was published on February 7, 2024.

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In this episode:0:46 Borrowing tricks from cancer could help improve immunotherapyT cell based immunotherapies have revolutionised the treatment of certain types of cancer. However these therapies — which involved taking someone’s own T cells and...

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