Caralluma fimbriata: A famine food that suppresses appetite and the clinical data can't decide if it works

Indian tribal communities have consumed Caralluma fimbriata during famines specifically as an appetite suppressant for centuries. The traditional evidence is ethnobotanically robust. But modern clinical trials show mixed results some positive for waist circumference reduction, some failing on primary endpoints. The gap between consistent traditional use and inconsistent clinical trials suggests the standardisation may not capture the right active fractions.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/34758791/https://pubmed.ncbi.nlm.nih.gov/17097761/https://pubmed.ncbi.nlm.nih.gov/33762661/