Challenging Cases with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) episode artwork

EPISODE · Jul 21, 2025 · 22 MIN

Challenging Cases with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

from Oncology Brothers: Practice-Changing Cancer Discussions · host Oncology Brothers

Welcome to this episode of The Oncology Brothers! Drs. Rahul and Rohit Gosain dived into the complexities of relapsed refractory diffuse large B-cell lymphoma (DLBCL) with their new series focused on challenging real-life cases.In this episode, we are joined by esteemed guests Dr. Carla Casulo from Wilmot Cancer Center and Dr. Tara Graff from Mission Cancer and Blood Center. Together, we explored the current standard of care, including R-CHOP and the role of bi-specific antibodies like epcoritamab and glofitimab.Key topics covered included:• When to use bi-specific antibodies and how to manage side effects• The importance of MRD monitoring in treatment decisions• Insights on patient management in community oncology settings• The evolving landscape of treatment options for DLBCL, including CAR-T therapy and clinical trialsWe also discuss practical considerations for community oncologists, including the management of cytokine release syndrome (CRS) and the role of immunoglobulin therapy in patients with low IgG levels.Whether you're a healthcare professional or someone interested in the latest advancements in oncology, this episode is packed with valuable insights and expert opinions.YouTube: https://youtu.be/05ieIyAIx_8Follow us on social media:•⁠ ⁠X/Twitter: https://twitter.com/oncbrothers•⁠ ⁠Instagram: https://www.instagram.com/oncbrothers•⁠ Website: https://oncbrothers.com/Don't forget to like, subscribe, and share your thoughts in the comments! Let us know if there are specific scenarios you'd like us to cover in future episodes.

Welcome to this episode of The Oncology Brothers! Drs. Rahul and Rohit Gosain dived into the complexities of relapsed refractory diffuse large B-cell lymphoma (DLBCL) with their new series focused on challenging real-life cases.In this episode, we are joined by esteemed guests Dr. Carla Casulo from Wilmot Cancer Center and Dr. Tara Graff from Mission Cancer and Blood Center. Together, we explored the current standard of care, including R-CHOP and the role of bi-specific antibodies like epcoritamab and glofitimab.Key topics covered included:• When to use bi-specific antibodies and how to manage side effects• The importance of MRD monitoring in treatment decisions• Insights on patient management in community oncology settings• The evolving landscape of treatment options for DLBCL, including CAR-T therapy and clinical trialsWe also discuss practical considerations for community oncologists, including the management of cytokine release syndrome (CRS) and the role of immunoglobulin therapy in patients with low IgG levels.Whether you're a healthcare professional or someone interested in the latest advancements in oncology, this episode is packed with valuable insights and expert opinions.YouTube: https://youtu.be/05ieIyAIx_8Follow us on social media:•⁠ ⁠X/Twitter: https://twitter.com/oncbrothers•⁠ ⁠Instagram: https://www.instagram.com/oncbrothers•⁠ Website: https://oncbrothers.com/Don't forget to like, subscribe, and share your thoughts in the comments! Let us know if there are specific scenarios you'd like us to cover in future episodes.

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Challenging Cases with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

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This episode is 22 minutes long.

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This episode was published on July 21, 2025.

What is this episode about?

Welcome to this episode of The Oncology Brothers! Drs. Rahul and Rohit Gosain dived into the complexities of relapsed refractory diffuse large B-cell lymphoma (DLBCL) with their new series focused on challenging real-life cases.In this episode, we...

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