EPISODE · Jun 10, 2026 · 36 MIN
Chasing Goals, Not Ghosts: Mireille Siné on Running 200 Miles with Lupus
from Invisible Strength · host Karin Wagner and Chris Burton
Lupus put her in the ICU in college. She came back to run 14 marathons, 5 ultras, and 200 miles from Boston to NYC.Run coach Mireille Siné on training with autoimmune disease — flares, fatigue, and the mindset shift that changes everything.In this episode of Invisible Strength, Karin and Chris talk with Mireille Siné — certified run coach, AIP nutrition coach, and the first Black woman to run 200 miles from Boston to New York City. Mireille shares her full story: the college stress that preceded her lupus diagnosis, the blood clot that took three ER visits to catch, chemotherapy and medical leave, and the slow, deliberate comeback that started with a quarter-mile run.We get practical: how Mireille structures training around flares with her stoplight protocol, why sleep is her non-negotiable recovery anchor, how she approaches nutrition and meal prep for inflammation, and how to tell normal training fatigue from the start of a flare. Plus the mental game — why "you're not gonna get anywhere chasing a ghost," and what invisible strength means to her.✨ FREE QUIZ: Not sure where to start on your own health journey? Take our free quiz → https://invigorateyourjourney.com/quiz/⏱️ CHAPTERS00:02 Meet Mireille02:02 Training with compassion04:08 The lupus diagnosis story09:14 Coming back: the first mile13:04 Self-doubt and setbacks16:01 The marathon that means the most22:01 Sleep, nutrition, community26:54 Coaching autoimmune athletes30:23 The stoplight protocol for flares34:14 Fatigue vs. flare: how to tell35:39 "Chasing a ghost" — the mindset shift40:44 What invisible strength means42:25 What's next for Mireille🌱 Community, resources & coaching: https://www.invigorateyourjourney.com🏃🏾♀️ Mireille: @heycoachmireille and https://www.coachedbymireille.com/ 🎧 Subscribe for real conversations around: Lupus, autoimmune disease, chronic illness, healing, fatigue, mindset, movement, resilience, and invisible illness support.💬 COMMENT BELOW: What's something people don't understand about living with chronic illness?#Lupus #ChronicIllness #AutoimmuneDisease #InvisibleIllness #LupusWarrior #LupusAwareness #HealingJourney #ChronicFatigue #ChronicIllnessSupport #AutoimmuneSupport #InvisibleStrengthPodcast⚠️ Disclaimer: This content is for education and shared experiences only and is not medical advice. Always consult your healthcare team before making changes.
What this episode covers
Lupus put her in the ICU in college. She came back to run 14 marathons, 5 ultras, and 200 miles from Boston to NYC.Run coach Mireille Siné on training with autoimmune disease — flares, fatigue, and the mindset shift that changes everything.In this episode of Invisible Strength, Karin and Chris talk with Mireille Siné — certified run coach, AIP nutrition coach, and the first Black woman to run 200 miles from Boston to New York City. Mireille shares her full story: the college stress that preceded her lupus diagnosis, the blood clot that took three ER visits to catch, chemotherapy and medical leave, and the slow, deliberate comeback that started with a quarter-mile run.We get practical: how Mireille structures training around flares with her stoplight protocol, why sleep is her non-negotiable recovery anchor, how she approaches nutrition and meal prep for inflammation, and how to tell normal training fatigue from the start of a flare. Plus the mental game — why "you're not gonna get anywhere chasing a ghost," and what invisible strength means to her.✨ FREE QUIZ: Not sure where to start on your own health journey? Take our free quiz → https://invigorateyourjourney.com/quiz/⏱️ CHAPTERS00:02 Meet Mireille02:02 Training with compassion04:08 The lupus diagnosis story09:14 Coming back: the first mile13:04 Self-doubt and setbacks16:01 The marathon that means the most22:01 Sleep, nutrition, community26:54 Coaching autoimmune athletes30:23 The stoplight protocol for flares34:14 Fatigue vs. flare: how to tell35:39 "Chasing a ghost" — the mindset shift40:44 What invisible strength means42:25 What's next for Mireille🌱 Community, resources & coaching: https://www.invigorateyourjourney.com🏃🏾♀️ Mireille: @heycoachmireille and https://www.coachedbymireille.com/ 🎧 Subscribe for real conversations around: Lupus, autoimmune disease, chronic illness, healing, fatigue, mindset, movement, resilience, and invisible illness support.💬 COMMENT BELOW: What's something people don't understand about living with chronic illness?#Lupus #ChronicIllness #AutoimmuneDisease #InvisibleIllness #LupusWarrior #LupusAwareness #HealingJourney #ChronicFatigue #ChronicIllnessSupport #AutoimmuneSupport #InvisibleStrengthPodcast⚠️ Disclaimer: This content is for education and shared experiences only and is not medical advice. Always consult your healthcare team before making changes.
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Chasing Goals, Not Ghosts: Mireille Siné on Running 200 Miles with Lupus
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