EPISODE · Feb 28, 2025 · 35 MIN
Chronic Leukemias
from Ninja Nerd · host Ninja Nerd
Send us Fan MailNinja Nerds,Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Chronic Leukemias, focusing on their pathogenesis, clinical features, and modern treatment strategies. We compare Chronic Myeloid Leukemia (CML) and Chronic Lymphocytic Leukemia (CLL), discussing the role of BCR-ABL in CML and the implications of smudge cells and monoclonal B-cell proliferation in CLL. Our conversation covers key diagnostic tools such as PCR, flow cytometry, and blood smear findings, as well as cutting-edge treatment options like tyrosine kinase inhibitors (TKIs) for CML and targeted monoclonal antibody therapy for CLL. We also discuss disease progression, complications like Richter transformation, and indications for therapy in asymptomatic patients. This high-yield episode is perfect for both exam prep and clinical application—enjoy and support us below!Support the show
What this episode covers
Send us Fan Mail Ninja Nerds, Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Chronic Leukemias, focusing on their pathogenesis, clinical features, and modern treatment strategies. We compare Chronic Myeloid Leukemia (CML) and Chronic Lymphocytic Leukemia (CLL), discussing the role of BCR-ABL in CML and the implications of smudge cells and monoclonal B-cell proliferation in CLL. Our conversation covers key diagnostic tools such as PCR, flow cytometry, and bloo...
NOW PLAYING
Chronic Leukemias
No transcript for this episode yet
Similar Episodes
Mar 27, 2026 ·100m
Mar 12, 2026 ·45m
Mar 3, 2026 ·19m
Dec 25, 2025 ·82m
Oct 30, 2025 ·63m