CIRS, MCAS & Autoimmunity: What’s Really Driving Your Symptoms?

What happens when you’ve been diagnosed with CIRS, followed the protocol, and still don’t feel better?In this episode of the Gutsy Health Podcast, Dr. Stadler of Red River Orem joins the conversation to explore why chronic illness rarely fits neatly into a single diagnosis. They unpack the overlap between CIRS, autoimmunity, MCAS, food sensitivities, blood sugar dysregulation, cortisol, anemia, and neurological symptoms and why comprehensive testing can be critical for understanding what is actually driving a patient’s symptoms.They also discuss the importance of treating chronic illness in the right biochemical order, identifying underlying immune triggers, and helping patients understand their own bodies instead of becoming permanently dependent on a practitioner.TIMESTAMPS00:00 – When Your Tests Say “Nothing Is Wrong”01:00 – Meet Dr. Stadler of Red River Orem03:00 – Why CIRS Isn’t One-Size-Fits-All05:00 – Dr. Stadler’s Functional Medicine Background08:00 – Bridging Conventional and Functional Medicine09:00 – The Problem With Self-Diagnosing CIRS11:00 – CIRS vs. Neurological Damage13:00 – Why Chronic Illness Symptoms Overlap15:00 – Why Deeper Testing Matters16:00 – Autoimmunity Mistaken for CIRS17:00 – C4a, MMP-9 and Other CIRS Markers19:00 – Low MSH and Genetic Susceptibility20:00 – Where to Start With CIRS, Autoimmunity and MCAS21:00 – Stop Guessing and Start Testing22:00 – Treating Chronic Illness in Biochemical Order23:00 – The Role of Anemia and Iron25:00 – Finding the Triggers Behind Immune Dysregulation26:00 – Blood Sugar, Cortisol, Vitamin D and Anemia28:00 – MCAS, Histamine and Food Sensitivities30:00 – When You Seem to React to Everything32:00 – What Can Drive Gut Permeability34:00 – Should You Eliminate Every Reactive Food?35:00 – IgG Food Sensitivity Testing36:00 – Dr. Stadler’s Preferred Testing Lab38:00 – How Chronic Stress Affects Immune Function40:00 – The Blood Sugar–Cortisol Connection41:00 – Hypoglycemia, Adrenaline and Anxiety42:00 – Why Blood Sugar Dips Can Worsen Neurological Symptoms43:00 – What Your Neurons Need to Function45:00 – CIRS and Neurological Symptoms47:00 – Treating the Individual, Not Just the Diagnosis48:00 – MCAS vs. Histamine Dysregulation49:00 – Food Allergies vs. Food Sensitivities51:00 – Identifying and Addressing Immune Triggers52:00 – Teaching Patients to Manage Their Own Health53:00 – Why Are More People Chronically Sick?54:00 – Stress and Endocrine Disruptors55:00 – Sedentary Lifestyles and Immune Health56:00 – The Rise of Autoimmunity57:00 – Has Chronic Stress Become Our Normal?59:00 – Rebuilding the Body’s Adaptability to Stress1:00:00 – Managing the Stressors You Can Control1:01:00 – How to Work With Dr. StadlerRESOURCES & LINKS MENTIONEDRed River OremFor consultations with Dr. Stadler and the Red River Orem team.Phone: 801-691-1765ImmunoLabsMentioned by Dr. Stadler as a laboratory he has used for IgG food sensitivity testing.Connect with the Gutsy Health PodcastFollow and message the Gutsy Health Podcast on Instagram with topics you’d like Dr. Stadler to cover in future episodes.Send us Fan Mail