Clinical Conversations (CE): Recorded Pharmacist Series: Toxidromes

Pharmacists providing care to patients following toxicologic ingestions of medications and other substances are often relied upon for treatment and monitoring recommendations. Many pharmacists do not routinely care for patients following toxicologic ingestions of medications or other substances and are unfamiliar with clinical presentation of various toxidromes and ultimately management strategies. This episode covers anticholinergic, cholinergic, sedative-hypnotic, opioid, sympathomimetic, serotonin syndrome, neuroleptic malignant syndrome, and malignant hypethermia toxidromes and discusses the clinical presentation and causative medications/substances and general treatment approaches, with an emphasis on antidotes for specific toxidromes including physostigmine, naloxone, flumazenil, atropine, and pralidoxime. CE expires two years from when this episode was originally published. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.