Clitoxin: The Clitoral Injection of IncobotulinumtoxinA for the Improvement of Arousal, Orgasm & Sexual Satisfaction episode artwork

EPISODE · May 13, 2024 · 20 MIN

Clitoxin: The Clitoral Injection of IncobotulinumtoxinA for the Improvement of Arousal, Orgasm & Sexual Satisfaction

from The Vagenius · host Red Alinsod, MD

This current newsletter is for providers looking for a solution to improve female sexual health and function. Dr. Runels and I welcome your sharing of this. This is free. Thank you Charles and Alex for entrusting me with getting the word out.If you are licensed by Dr. Runels to provide O-Shot and Vampire Procedures then this will be a huge bonus for you. For no fee, do the online training and get approved to add Clitoxin to your list of procedures to improve women’s sexual function. You have to be an active and paying member of Cellular Medicine Association for this privilege, For those who have not been trained to provide O-Shot and Vampire treatments, are not members of CMA, you can go HERE for training and licensure:Module NS1: Synergy O-Shot and RF Training This newsletter is in two sections. This beginning top section (Part 1) is for the Provider. It is the science behind Clitoxin. The later part of this newsletter (Part 2) is geared for the patient, the Lay Public. Part 1Clitoxin Summary of Mechanism of Action…After Injecting botulinum neurotoxin (BoNT) into the clitoris, it is thought that (1) it is taken up by endocytosis and then migrates by axonal transport to the ganglion embedded in the wall of the vagina; (2) these ganglia then signal (through afferent autonomic nerves in the inferior hypogastric plexus) to trigger the hypothalamus (where the arousal center resides); (3) the activated hypothalamus triggers (through efferents going back to the genitalia and to the cerebral cortex) arousal, desire, and lubrication, and facilitate orgasm, combining to increase sexual satisfaction in the woman. This is in addition to the neovascularization, neurogenesis, and local vasodilation triggered by the BoNT. These effects can be amplified when the BoNT is combined with the regenerative properties of platelet-rich plasma.AbstractAccepted treatments for female sexual dysfunction (FSD) are currently limited to psychological, hormonal, surgical, and psychopharmacologic interventions. There are no FDA-approved pharmaceutical interventions that directly affect the female genitalia to improve female sexual function other than prasterone for dyspareunia. Botulinum neurotoxin type A (BoNT) has been shown to improve erectile function in men by increasing arterial blood flow and possibly by increasing parasympathetic tone. In all previous studies in women, BoNT has only been used to improve sexual function by either attenuation of sensation or of muscle contraction and never to accentuate sensation, desire, orgasm, lubrication, or satisfaction directly. This pilot study was undertaken to test the effects, if any, of the clitoral injection of BoNT on female sexual function. The female sexual function index (FSFI) was used as a measure. Our data indicate that the treatment enhances sexual function in women in multiple domains—including desire, arousal, lubrication, orgasm, satisfaction, and overall sexual function. The benefits to overall sexual function improved by an additional 50% when the BoNT was combined with platelet-rich plasma (PRP) rather than saline alone. Our population was small, and placebo effects are possible; but the effects of treatment resulted in improvements in FSFI greater than previously reported after treatment with any of the currently FDA-approved drugs for female sexual dysfunction. The extended safety profile of BoNT for women of reproductive age at the dosages used, the known regenerative properties of BoNT and PRP, its positive effects on circulation and the autonomic nervous system, and the lack of any FDA-approved therapies that directly affect the female genitalia to improve sexual function warrant offering this innovative treatment to women suffering sexual dysfunction unresponsive to other means.Download the original research PDF:Part 2CLITOXIN: The Explanation for Patients:Important Legal Disclaimer: This is an off-label use of botulinum toxin; no results are ever guaranteed (no therapy works every time). If considered, it should only be done by a physician who has been properly trained and certified to do the procedure and only after considering all other options, including the option to do nothing, and only after a signed consent that includes the fact that results may vary and are unpredictable for new, off-label therapy and includes all the usual contraindications and possible side effects of botulinum toxin. Click on “Clitoxin” below to see more of the research:I hope you have enjoyed this newsletter and have learned some new things to help your practice. I always welcome your input and inquiries. Email me directly. Tell your colleagues of this resource on Cosmetic Gynecology.Social Media:Follow my Social Media adventures below as I educate and entertain every week. I will integrate my Newsletters with Social Media and Podcasts.Instagram: VageniusMDFB: Vagenius - Red Alinsod, MDTicTok: VageniusMDWebsites:Alinsod InstituteGynflixDALLAS OFFICEAlinsod Institute DallasWomen’s Wellness Institute of DallasPreston Sherry Plaza8201 Preston Road Suite 520Dallas TX 75225Phone: 945-900-7576Contact:Dr. Red Alinsod: [email protected] VEGAS OFFICEAlinsod Institute Las Vegas2990 W. Horizon Ridge Parkway, Suite 100Henderson, NV 89074Phone: 945-900-7576Contact:Dr. Red Alinsod: [email protected] you for reading Cosmetic Gynecology Newsletter. This post is public so feel free to share it.Cosmetic Gynecology Newsletter is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit cosmeticgynecology.substack.com/subscribe

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