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Confronting AI’s Next Big Challenge: Inference Compute episode artwork

Aug 6, 2025 24 min

Confronting AI’s Next Big Challenge: Inference Compute

from The New Stack Podcast Hosted by d-Matrix, Sid Sheth, The New Stack, Heather Joslyn

While AI training garners most of the spotlight — and investment — the demands ofAI inferenceare shaping up to be an even bigger challenge. In this episode ofThe New Stack Makers, Sid Sheth, founder and CEO of d-Matrix, argues that inference is anything but one-size-fits-all. Different use cases — from low-cost to high-interactivity or throughput-optimized — require tailored hardware, and existing GPU architectures aren’t built to address all these needs simultaneously. “The world of inference is going to be truly heterogeneous,” Sheth said, meaning specialized hardware will be required to meet diverse performance profiles. A major bottleneck? The distance between memory and compute. Inference, especially in generative AI and agentic workflows, requires constant memory access, so minimizing the distance data must travel is key to improving performance and reducing cost. To address this, d-Matrix developed Corsair, a modular platform where memory and compute are vertically stacked — “like pancakes” — enabling faster, more efficient inference. The result is scalable, flexible AI infrastructure purpose-built for inference at scale. Learn more from The New Stack about inference compute and AI Scaling AI Inference at the Edge with Distributed PostgreSQL Deep Infra Is Building an AI Inference Cloud for Developers Join our community of newsletter subscribers to stay on top of the news and at the top of your game

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While AI training garners most of the spotlight — and investment — the demands of AI inference are shaping up to be an even bigger challenge. In this episode of The New Stack Makers, Sid Sheth, founder and CEO of d-Matrix, argues that inference is anything but one-size-fits-all. Different use cases — from low-cost to high-interactivity or throughput-optimized — require tailored hardware, and existing GPU architectures aren’t built to address all these needs simultaneously.

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Confronting AI’s Next Big Challenge: Inference Compute

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