Contraline's ADAM in the clinic: towards a new era of male contraception?

When it comes to contraception, most of the innovation in the last century has focused on providing contraceptive alternatives for women. The contraceptive pill was approved by the FDA in 1960, the first IUD approved in 1968, and the female condom in 1993. For men, however, there has been little advancement since the invention of the rubber condom in 1855 and the first vasectomies in humans around the turn of the 20th century.Contraline is a biotechnology company that is aiming to change that record. They are currently heading into Phase II trials with a therapy that they claim is reliable, long lasting, easy to use, and reversible. This week, I talk with Kevin Eisenfrats, CEO of Contraline, about the challenges of bringing a new contraceptive to market, how to manage clinical trials on multiple continents, and what the world might look like if the contraceptive burden passes from women to men.01:21                      Kevin Eisenfrats and Contraline07:28                      Contraline’s ADAM09:09                      How ADAM works11:39                      Reversibility is a differentiator for ADAM14:01                      Hormonal gels and contraception17:14                      The phase I trial in Australia21:47                      The implantation process25:07                      Moving into phase II27:04                      The male contraception market29:30                      Fundraising for male contraception33:06                      The gendered burden of contraception34:54                      The future of male contraception36:49                      The cultural and social impact of male contraceptionInterested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletterTo dive deeper into the topic: MedinCell Granted €17M to Develop Cheap Long-Acting ContraceptionInpart Connect: Reversible Male ContraceptiveInpart Connect: Cyclic Peptides as Non-hormonal Male Contraceptive Agents and Methods of Use ThereofInpart Connect: Noninvasive Laser Vasectomy