Could Ketamine Unlock a New Era in Mental Health? with Dr. John Krystal episode artwork

EPISODE · Oct 28, 2025 · 42 MIN

Could Ketamine Unlock a New Era in Mental Health? with Dr. John Krystal

from Neural Compass

What happens when decades of groundbreaking neuroscience challenge everything we thought we knew about depression?In this episode of Neural Compass, Dr. John Krystal—Chair of Psychiatry at Yale and the scientist whose lab discovered the rapid antidepressant effects of ketamine—joins Jimini’s Mark Jacobstein to explore how novel treatments are reshaping the future of mental health.They cover:- The story behind ketamine’s unexpected antidepressant effects- Why depression may be rooted in the cortex—not just monoamines- How synaptic regrowth fuels resilience and recovery- The promise and perils of psychedelics as clinical therapiesLearn more: jiminihealth.com

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Could Ketamine Unlock a New Era in Mental Health? with Dr. John Krystal

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